The genesis of action
is the role of the upper motor neuron which happens in the motor cortex of the cerebrum. In
the spinal cord, the upper motor neuron structurally traverses to
rendezvous with the lower motor neuron,
which electronically conveys the instructions to the skeletal muscle. In a nutshell, the upper motor neurons brainstorms
the movement, while the lower motor neuron executes the instructions by
triggering skeletal action.
are multi-taskers as they perform diverse roles from logistical support thru
the shipment of nutrients, juggling the correct ion concentration and
reconstruction during neuronal damage. Due to the core function of astrocyte
with repair and maintenance, reactive astrongliosis as response to injury and
infection is a hallmark feature of CNS disturbance.
Microglia is the “Cookie Monster” of the central nervous
system which gobbles up plaques, injured neurons, synapses and pathogens in the central nervous system.
The microglial antipodal extremes of low activity (Autism) to over activity (Alzheimer’s)
pathological effects. Too many connections of neurons can overwhelm the
senses and explains the hyperactivity of autistic individuals.
Oligodendrocytes produces myelin
sheath to cover
axons as insulation in the central nervous system. Lack of myelination occurs
when oligodendrocytes die, and unmyelinated neurons cannot function properly as
seen in multiple sclerosis.